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Available data suggest that both the estrogenic and antiestrogenic properties of clomiphene may participate in the initiation of ovulation. The two clomiphene isomers have been found to have mixed estrogenic and antiestrogenic effects, which may vary from one species to another. Some data suggest that zuclomiphene has greater estrogenic activity than enclomiphene. Clomiphene citrate has no apparent progestational, androgenic, or antiandrogenic effects and does not appear to interfere with pituitary-adrenal or pituitary-thyroid function. Although there is no evidence of a "carryover effect" of Clomid, spontaneous ovulatory menses have been noted in some patients after Clomid therapy. Based on early studies with 14 C-labeled clomiphene citrate, the drug was shown to be Anastrozole absorbed buy where to get clenbuterol">orally in humans and excreted principally Arimidex tabs the feces. Some 14 C label was still present in the feces 6 weeks after administration. Subsequent single-dose studies in normal volunteers showed that zuclomiphene cis has a longer half-life than natural legal testogel online in uk">enclomiphene trans. Detectable medical cart">levels of zuclomiphene persisted for longer than a month in these subjects, Anastrozole 1mg pills. This may be suggestive of stereo-specific enterohepatic recycling or sequestering of the zuclomiphene. Thus, it is possible that some active drug may remain in the body during early pregnancy in women who conceive in the menstrual cycle during Clomid therapy. There were a total of pregnancies reported during the clinical trial period. Of those pregnancies, information on outcome was only available for of the cases. Table 1 summarizes the outcome of these cases. Of the reported pregnancies, the incidence of multiple pregnancies was 7.




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